Systemic and metabolic effects of PDE5-inhibitor drugs
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چکیده
منابع مشابه
Adipogenic and Metabolic Effects of Antipsychotic Drugs
Overview: Though possessing many advantages, many Antipsychotic drugs (APDs) have a major liability in their ability to promote adiposity, obesity, and metabolic dysregulation in an already metabolically vulnerable population. The past decade has witnessed substantial research effort aimed at quantifying, understanding, preventing, and alleviating these adverse effects and our goal is to provid...
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OBJECTIVE The main objectives are to present the different adverse effects of the immunomodulatory drugs that can impair the quality of life of the immunosuppressed patients and study the impact of immunomodulation on oral diseases. Immunomodulatory drugs have changed the treatment protocols of many diseases where immune functions play a central role, such as rheumatic diseases. Their effect on...
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It has been shown that the renin-angiotensin system (RAS) plays key roles in the inflammation process. Imbalance in the oxidant-antioxidant system is one of the major causes of inflammation. In the present study, the effects of captopril on total and differential WBC, oxidative stress in systemic inflammation produced by lipopolysaccharide (LPS) were investigated. The rats were divided to: cont...
متن کاملLocal versus systemic effects of inhaled drugs.
For all drugs, the therapeutic ratio, i.e., the difference between therapeutic effect and adverse effect, should be as large as possible. When focusing on drugs used in the treatment of asthma, particularly beta 2-agonists and corticosteroids, the therapeutic ratio of these drugs can be considered to be the degree of separation of their effects on lung function from their systemic effects. This...
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ژورنال
عنوان ژورنال: World Journal of Diabetes
سال: 2010
ISSN: 1948-9358
DOI: 10.4239/wjd.v1.i1.3